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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44a0bebc52bf0b20e2237d64a1ac8ceb927b69c91c52ef1d91b5678b2af06efe' 
  AND token = 'hzQxmUbqN7ZCA9R3tlzObah2nEfkRN0u+4TXQ4C+6TU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}