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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15da29e008825b7a2a777632de01c74e3836ae9cca0ad2a8287bd17e9eb5965d' 
  AND token = 'fKTUuZ3Pq48+TznRzt2gp0sP+L51zRhZsC/fdol9hec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}