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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8e1a0fcc6f81315d05c0bd2e9f6356e63808e43d81b9422fca2a59bebab9c6' 
  AND token = 'jCWRNI+9HAW0+ynh4ZVNVhX8WBnboVa5UDwXjg8bVTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}