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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d66e33c075da4628fa868013d33989a57d3c7c9b8cfd805d186eef2a621a5f6' 
  AND token = 'F37odwgS/kZyzkyTvxPMT3NUmMAYa3VwnS1qxAChO7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}