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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22b37c4df96f3d36d143786a72a28cd1bb27ab6610b24d3c6080b64a9fd6f05' 
  AND token = '01nLhQqhEVmpQ4H3p08dCThUw8U+n2PpzO5i74Cmn0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}