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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1821e14100730bbf866bddf142c48c35f9d08f208ef18e4d3ca5468b185b2b3c' 
  AND token = 'v7rs/UIm96EAAyFJ4r/EVBwHh/vxVBJWXXkNVkRmoiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}