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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1832f9ff0cfcf4a13e56b93a2de3a38cf7074ad8112fca2147f9f1406ee03949' 
  AND token = 'HzUCBZgrsokFAPjFhEtl6vXLO4PEtcHaMW0b+LXBe9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}