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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51f22b860a6eb164e54d52ef6a7bf29e03083e00a1a8f7742b50c69bbe6d11d1' 
  AND token = 'V/OlXgkI+kVuTk8Ekja7CG+KIa0V4rMqgiWSZ5PeFuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}