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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb7452e4d49ffccd5bf82eca9be0d9f151c7e8725219e9104dc3b5e85a8db9bb' 
  AND token = 'OP+z3iLvlsOCosCkG0u2exWuAxZmVaSUxSXmzOdDs8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}