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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c38f65e06126ff60cb303085563e221258e51285521d07896d9028143ee92be9' 
  AND token = 'hiU/VnVO0fuEH+jkC3BUaAs6bXW8Vh0hRhx/KfsWfjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}