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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b1f448a2afde3aab8c2ed33048af1dbf51f510ae83b6afcf83f92704de46766' 
  AND token = 'M3vxIHJSxTbMDpCC9oi6TqeUBGZQAN95jFSFjEmSQdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}