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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef656950f46fc9012d7c4c9262f31bf840bde139b23aa88bf9416600fec303d5' 
  AND token = 'NN2BV07DA45IlspoVthbi72y0su/w6m7xsaF1WISgc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}