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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8eaee3832ebae5c80c4487e06ca132ec82726c1af90f0b73ff65c997c2771f8' 
  AND token = 'KkgFjrMzbEGfh2xa3x/UPQhggqMz0GT04BHmdGvx0UM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}