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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d4026f16aeea785448c7d6db6c8db1d6ee6e9d6e3eec08b5ad8b7912b358798' 
  AND token = 'pywXjYb5GoSUFM3E0XTudK9ediUqtO5tC2bWV0KUQBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}