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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '557c53aeec9b8db427a63d1adb26f63e727c67ac05e677cfe8fc7fc09b2369d5' 
  AND token = '0YurE7j/bCh4vYgDTtSp3D4RAxrCE9VNi49F9nittyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}