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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '395fa696f4a469625fac086adfc1f4fa6c4b1c125f6d830d9419717d9409c7d7' 
  AND token = 'E/Ba3pP8GlJo9VbrDtzBC0tBCkNr/zVJNxDd3zqzpqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}