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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecaa902155c8c81bc67d26eff6a64639e3a685e1bbb66a0e948ffb67bd786e38' 
  AND token = 'EH4sA8xlM7mfDB5bt5b0APW8JsfpmMR0Zpbw+G7bNYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}