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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c3f47e2505073a2f8ca651605fbd5b307ac5b51c653d643c573da752f44aa39' 
  AND token = 'fUWQUSwD/Fnr9XSeMTtloZEJggbK0QIn501vvaLgvRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}