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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11498ff1afebef942d8249ecb27ca296bb86d05fd9b02e29911bd236c86e136b' 
  AND token = 'eThtIaNyF8MRDkX3+gC08zs1wkHfCIUBOatiIM1GJek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}