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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb9f946b9f513149665d8b1b50f18f6c93600818b5ba0b881a8f4781671d6fa5' 
  AND token = 'WS7GkQParEXg4kYZ39TSf1U1MSIcPcBT/D/NxvqCAhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}