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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456e29c5518d6c4318f918436bbea0c0c234e7ccd3bef1ba79e7173434476583' 
  AND token = 'd7DFS1EqAhE/mD29XYy3Zr4pAUpi7z6S1+LUHS1VyTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}