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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb45e6469fdca03195be8bd3256ac9c54d1857d3b4d765f3a44f2a82eb9ae05c' 
  AND token = 'aa5r2/Uv+XIK1W/kIpLpQsoQP9HFFqOV5FSaMAS0x2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}