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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6347f00d854cca3cd6245c8141beb2a6fde8835350d86f1ff19b6e17bffb57d4' 
  AND token = 'L+LwPnwl1RwLPzwwb0Fz9goCe+v1IUVL6Bm42tWYl3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}