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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '209c874529e4dd241e2ed9e68c6e97fed68be3ac2e06732b24f50ade77957d54' 
  AND token = 'FNppV/zxNzt4XhSKXhSFQqYh6suWJEyDzKbv0y8qimM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}