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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3aeb945120061c96e5fd23b94adb5be0cff844e78a38558ea4313b51887f04ac' 
  AND token = 'JbjxhcOQnFyK4p0PDKWrPXEmwA9E5h5BntEobuBiL8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}