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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78674e26ac022d3f0660ead3b3b09b30d5b5553006cf65286bf6804a13bf2c98' 
  AND token = 'CR5WjxgQinLMSLQ/103Ba+MxUtVKJ3phGc9Gl36wmok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}