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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82684e1715f0823960c51363e490722b4f0b05dc43b93a25c0f7b93e7d1da25e' 
  AND token = 'MZdzZ3Fqyp8BzuXFOqOAZ9oS0+IPK9kv1/oks4mUA2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}