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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e9985e1577e036de2854a6c12961f69acae5d3c55b665b22e983faea6af4e4d' 
  AND token = 'U9h1pRumul7K9eDNTYU/T/bl8cZllQd0k7kG9AMYjmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}