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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e28d712381c642c3b643166132475f9afb860e97c917852833e6774e5506874d' 
  AND token = 'irF1xCN8IO/FI6iY2t27T45uwRuWLjCsReqK6QFVClE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}