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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc52531c7735ae87842e972d9c3231a67b966b808099a5c2e53e36f6efb80a3f' 
  AND token = 'uMx0W+wlkOaGtGB9awOQ+e+xQdi8EtgHEE/fii5BtCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}