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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41505b47ba4605dbccd6f0dcace2ec40cbe91fd8f8e22a5d8367312a2a13a41e' 
  AND token = 'lJfPY5r/7atxpaF/rXD/K1YUDrEv4A75Iu7JsoneBu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}