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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66b408cda8fc0636dad468900cadd3e2d9c0be49f1a2cb8865619333f53739c6' 
  AND token = '9/LWjF8r9dsTTYE49VjBKxSi4EOeXPmTqOeZp/b9a5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}