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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb4d15e06597da8aa5458f58ea5f4798177b49e9a9857194ca07d347635b1916' 
  AND token = 'gftq06m4BP46egDqiezceIX9+v5y3G8dg1vHS8UuRuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}