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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dd4f6eeadea38019990c7d85c4b8c9cafdee80976e3f8db58f890d91742716e' 
  AND token = 'v3+q2xpVnqY06OydzkiD1VCuAredDf4ekGEbGzWjxAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}