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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68e966dd929ab060d2cdb5b2f43b364900866aa251465ce853e3124d971a261f' 
  AND token = 'GA5ior/f0UqXSijLD+SsXKu4zSQOJDn+xbN4zy6yR3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}