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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a67e1419aee9433e067492a7ef0e17c6ce956dcd508d3426be9a0e177f1372f' 
  AND token = 'bHl1p1ozaJePSBkJQAHxzEf/zkYBODIf1DDW4nE1BOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}