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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0109268b21f288d64e55221f771675ff1e0122cd309717cdda99efb4074f743' 
  AND token = 'N4qBDDOsgtDs4nHwnVJ8YEHDSwEpvuU66dRFCQFU5AI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}