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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdf69f5829513fc374f8ff393c9a67f4b03073c589a5daaa536bc553b26a466f' 
  AND token = '4ODpFfoS0O8f9uuiW5LtdhfXZ6fO4pzdvhVKy73Ngtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}