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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2298f5d8e561fa6e7b3a6627d402a127da437c1b0814edb992eeeb6273f5abb' 
  AND token = 'iQSCdNPdGFQS34/rCV1nNmjU+CP2s3bNfqKMQA0oKIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}