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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a32ebe9a7e6c6e34bb8297b72777004041b9b1a8a5d6da2d297a1e773f59dcfe' 
  AND token = 'HOpYAjH87Pg8efTeoV7AsTkx4BzCRCAp+XkGqm/6UhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}