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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c18c4c1be7e9ea3361b86ad19735f3a4afcadf2326684aa6929f181105cbfc0' 
  AND token = 'LteNK+rMfOY+Z2x1yTcoouTQQIn3vJOs33dQC3OKNek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}