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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cadbc9d140d2d1b5aafdf9b4a5fe727098be00505a3e0946fe2f82efec503d5a' 
  AND token = 'bAYXtfz3dUBsXGszv6LRSM9qm3Djv9IC1jMjgoVPn38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}