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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '403401e0a051cb5617012412aa81795d67c249f0e212e00615e925dcc0debf0f' 
  AND token = 'iPtF49gqIXvnSIk2AYAwYK1N/B49+KZPL09/3trBBAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}