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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f757b9575af96105621a957cdcc56c378296d66070c217462181e03db0f9bc81' 
  AND token = '7IH1JqHCTJlutZPyhEMDlbG7JRr5dGmqq0UWfuVQR7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}