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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1627ec1ffebdf33f08e60d28ece2d931b175e92ae457cf043a7afa615a42f252' 
  AND token = 'ZkKezBZdZ1EE29qE1e+WyfVrYV4GLvaNYzSX+/3ZwS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}