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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '991a2813e9688863e929395ab3fb20a82c081b9e6f4f4e0eedb29ad4aa1f5121' 
  AND token = 'J9RM2kU5ZHrOxv1sfmegL9v8B0GAe/M8FhuBGN3PXLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}