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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6538494eb65ea8e3c7515e7b4de440c0f964673150cb4ce1680cebe49a8dce8d' 
  AND token = '3+rQESHtDSL++OrnqE1coe2co61rXZc/uFoz8Jp/Ft0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}