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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '544b00fe730fb8529904a19d821e036254e246656b14cd40ecce8b7b750e5354' 
  AND token = 'rMq/1QPAu30RSG5CUVbh9EEAw3ltX3ROg1yMR5MVc6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}