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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10902084726e729e53c28b7e7a46fbd666e9d74d0cdd37fe77ec63e3f13b82d7' 
  AND token = 'C3ERhNey8e0BFtbcDn+EL36IPT+CEn63OpIgCvYIC1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}