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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ea998c89d86384549d8dd56d09e174d4351c654be5a33aa7af10338032049fa' 
  AND token = 'zmE2nrkONW++65DIUEubGyOs5WPBPe3kbFrklPo6fUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}